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艾美捷科技代理Gene Tools品牌


Gene Tools是一家生产和销售Morpholino Anti-sense oligos(反义寡核苷酸)的公司,其产品专门用于基因调控的科学研究和药物开发。Gene Tools公司由多位资深科学家组成,为全球客户提供免费的技术咨询和Morpholino 序列设计服务。 Morpholino作为基因调控研究的最佳工具,已被广泛用于:阻断靶mRNA 翻译 (下调基因);诱导RNA选择性剪接 (下调或上调基因);阻断 miRNA;阻断病毒 RNA;阻断 non-coding RNA。


Morpholino介绍

Morpholino属于第三代反义寡核苷酸,主要通过阻断蛋白质翻译过程而达到抑制目标基因功能的作用,目前已经广泛用于发育生物学和细胞学实验中,并取得了非常好的实验效果。

Morpholino以吗啉环类似物为基本骨架,这种独特的结构特性使得Morpholino 具有以下几个特点:

● 与其他类型的反义寡核苷酸相比,Morpholino 能更好地抵抗核酸酶的作用;

● Morpholino 与靶序列结合后通过空间位阻效应发挥作用, 不激活RNaseH,不引起目标基因mRNA 的降解 ;

● 针对翻译起始位点区设计的Morpholino 用于抑制蛋白质的翻译,针对 pre-mRNA 剪切位点区设计的Morpholino 可影响mRNA 剪切,得到不 同的转录本,可以方便地用于目标基因结构域的突变研究;

● 与靶序列结合能力强,可以渗入mRNA 的二级结构, 并且特异性好。

配合Morpholino 的使用,Gene Tools公司开发了相应的递送系统,可以安全、高效地将Morpholino 输送至胞内,因此,Morpholino 也可以用于遗传学研究和新药靶标的发现以及验证。此外,Morpholino 可以标上荧光基团、亲和标签以及活性反应基团,以供不同的研究需要。

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Gene Tools公司产品介绍

● Custom Morpholino:可以根据目标基因序列定制设计并合成Morpholino,用于体外细胞实验或某些直接显微注射的模型(如斑马鱼、非洲爪蟾胚胎)。

● Vivo-Morpholino:适用于活体动物模型(小鼠,大鼠,狗,灵长类等),细胞培养,器官培养等。通过特殊的末端修饰,提高了其穿透细胞膜进入组织细胞的能力,使得在成年动物(主要是小鼠、大鼠)中进行系统性基因功能研究成为可能。

● Prepared Control Oligos:根据特定需求合成细胞穿透肽偶联的 Morpholino。适用于活体动物模型(小鼠,大鼠,狗,灵长类等),细胞培养,器官培养等。


产品名称Short DescriptionOligo sequenceSKU
Standard Control Oligo Negative control oligoCCTCTTACCTCAGTTACAATTTATAPCO-StandardControl-100
Vivo-Morpholino Standard Control OligoNegative Vivo-Morpholino control oligoCCTCTTACCTCAGTTACAATTTATAPCO-VivoStandardControl-100
Random Control Oligo 25-N25-base random sequence mixtureNNNNNNNNNNNNNNNNNNNNNNNNNPCO-RandomControl-25N-100
Zebrafish p53 oligoDanio rerio apoptosis suppression oligoGCGCCATTGCTTTGCAAGAATTGPCO-ZebrafishP53-100
Zebrafish Chordin Positive Control OligoDanio rerio Chordin positive control oligoATCCACAGCAGCCCCTCCATCATCCPCO-ZebrafishChordin-100-F
Clawed Frog Beta Catenin Positive Control OligoXenopus laevis Beta Catenin antisense oligoTTTCAACCGTTTCCAAAGAACCAGGPCO-BetaCatenin-100-F
Green Fluorescent Protein Positive ControlTranslation blocker for GFP targetACAGCTCCTCGCCCTTGCTCACCATPCO-GFPControl-100
Vivo-Morpholino GFP Positive ControlTranslation blocker for GFP target (Vivo-Morpholino)ACAGCTCCTCGCCCTTGCTCACCATPCO-VivoGFPControl-100
Fluoresceinated Vivo-Morpholino Std ControlNegative Vivo-Morpholino control oligo with 5'FluoresceinCCTCTTACCTCAGTTACAATTTATAPCO-FluorVivoStandardControl-100-F


● Endo-Porter:为了解决Morpholino在体外培养细胞中摄取效率低的问题,Gene Tools 开发了 Endo-Porter 这种特殊的转染试剂。它通过温和的内吞体逃逸机制帮助Morpholino进入细胞质。



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艾美捷科技代理Lifeome品牌全系列产品


Lifeome公司致力于基因组学、转录组学及蛋白质组学领域的产品研发、生产与市场化,提供全方位的研究产品与服务体系。Lifeome核心产品包括生长因子、抗体、病毒蛋白、重组蛋白,基因工程克隆载体等。


Lifeome公司的服务

● 定制抗体开发服务:多克隆与单克隆抗体解决方案,应用于蛋白定量检测、细胞/组织定位分析(活体或固定样本),由政府认证实验室提供全流程生产服务;

 高端多肽合成解决方案:由平均从业5年以上的技术专家操作顶级合成系统,覆盖从基础科研到工业级生产需求;

● 蛋白质表达与纯化:其培养简便、产量高,能快速获得免疫原。


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Cytokines
Bone Morphogenetic ProteinBeta DefensinEndoglinInterleukinSerum Amyloid A
Leukemia Inhibitory FactorBetacellulinFlt3 LigandApoliproteinsThrombopoietin
B Cell Activating FactorAngiopoietinHedgehog ProgeinOthersTrefoil Factor
B type Natriuretic PeptideEBI3InterferonResistinVisfatin
Tumor Necrosis Factor



Chemokines
ENA 78IL-8 (CXCL8)MDC (CCL22)NAP-2 (CXCL7)SDF (CXCL12)
Lymphotactin (XCL1)IP-10 (CXCL10)MEC (CCL28)OthersTARC (CCL17)
Platelet Factor-4 (CXCL4)EotaxinMIG (CXCL9)GRORantes (CCL5)
I-TAC (CXCL11)MCPMIP

Recombinant Proteins
ADP-Ribosylation FactorCardiac TroponinSuperoxide DismutaseProfilinStreptavidin
Synaptosomal Associated ProteinChromograninHypoxia-Inducible FactorBIDHSP
TNF receptor-Associated FactorcJunU6 Small Nuclear RNAProtein-A, A/G & GSynaptobrevin
Microtubule-Associated ProteinAnnexinMelanoma AntigenRAS OncogeneAlbumin
Myelin Oligodendrocyte GlycoPAprotininCoaggulation FactorsCalbindinSyndecan
Translation Initiation FactorsCollagenCoagulation FactorsCell Division CycleSynuclein
B Cell LymphomaCrystallinMyoglobinCentromere ProteinThioredoxin
Beta 2 MicroglobulinCystatinMyosin Light ChainRibosomal ProteinThrombin
Programmed Cell DeathCytokeratinDNA-Damage ProteinSecretagoginAllergy
C-Reactive ProteinNanogNatural ProteinsSelectinTransferrin
Ras-Related C3 Botulinum Tox...Dynein Light ChainNon-Metastatic CellsSeptinTransgelin
Calcium Binding ProteinEphrinVisinin-Like ProteinSerpinAvidin
Small Nuclear Ribonucleo...ER ProteinsOuter Membrane ProteinCD AntigensTropomyosin
Chloride Intracellular ChannelFABPp53SirtuinTrypsin
Sex Determining Region Y BoxFerritinPCNASMADKiller Cell
Regenerating Islet-DerivedFibronectinPOU ClassCalmodulinUbiquitin
Regulator of G-Protein SignalingPrefoldinHigh-Mobility GroupStathminVimentin
Antibodies
Anti Human ChemokineAnti ViralAnti Human CytokineAnti Human EnzymesAnti Human HSP
Anti Human LymphocyteELISA PairsAnti Mouse LymphocyteAnti Expression TagsAnti Mouse Cytokine
Polyclonal Rabbit AntibodiesRare Antibodies


Viral Proteins
BorreliaEBVHepatitis CMalariaRubella
ChagasEncephalitisHepatitis DMeaslesS. Typhi
ChikungunyaWest NileHepatitis EMumpsSARS
ChlamydiaHantavirusHerpesMycoplasmaShiga Like Toxin
CytomegaloHBsAgHIVNorovirusToxoplasma
DengueHepatitis AHTLVPapillomavirusTreponema
EbolaHepatitis BInfluenzaParvovirusVaricella
Feline Leukemia VirusZika


Growth Factors
Melanoma Inhibitory ProteinsGalectinKeratinocyte GFOmentinProlactin
Colony Stimulating FactorGrowth HormoneLeptinOncostatin-MRANK Ligand
Hepatocyte Growth FactorCTGFMacrophage Migration IFOsteoprotegerinRetinol Binding P
Epidermal Growth FactorIGFBPActivinOthersStem Cell Factor
Transforming Growth FactorInsulinMyostatinPDGFErythropoietin
Fibroblast Growth FactorInsulin-like GFNogginPlacental LactogenVEGF
Research Reagents
Biochemical KitsCoVID19CRISPR-Cas9Media/PlatesMolecular Markers
Nucleic Acids PurificationSeamless Cloning


Primary Cells
DogGoatMouseRabbitRat
ELISA
ChemiluminescentHRPSpecialty Kits
Xpress Clones-cis Element Reporter
Bacterial ClonesMammalian Clones-Hygromycin KitsNeomycin Kits


Lifeome部分产品列表

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品名货号规格
Primary AC Cell, DogCSI003Ca01-500k5x10^5
Primary AEC Cell, DogCSI006Ca01-500k5x10^5
Primary AFC Cell, DogCSI008Ca01-500k5x10^5
Primary ASMC Cell, DogCSI153Ca01-500k5x10^5
Primary BMMC Cell, DogCSI164Ca01-500k5x10^5
Primary BMMSCs Cell, DogCSI083Ca01-500k5x10^5
Primary MC Cell, DogCSI007Ca01-500k5x10^5
Primary NDF Cell, DogCSI088Ca01-500k5x10^5
Primary NPC Cell, DogCSI113Ca01-500k5x10^5
Primary OB Cell, DogCSI102Ca01-500k5x10^5
Primary OF Cell, DogCSI138Ca01-500k5x10^5
Primary RCEC Cell, DogCSI067Ca01-500k5x10^5
Primary SEC Cell, DogCSI112Ca01-500k5x10^5
Primary TDSC Cell, DogCSI255Ca01-500k5x10^5
Primary TSMC Cell, DogCSI068Ca01-500k5x10^5
Primary AC Cell, GoatCSI003Cp01-500k5x10^5
Primary ASMC Cell, GoatCSI153Cp01-500k5x10^5
Anti-APOB100 AntibodyA90603Hu01-1100 ug
Anti-APOC2 AntibodyPAB77963-1100 ug
Anti-HPR AntibodyA92000Hu01-1100 ug
Antibody to Mouse Insulin (INS)A90448Mu01-100ug100 ug
Antibody to Mouse Insulin (INS)A90448Mu01-50ug50 ug



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Generon.png

在诊断领域,Generon拥有数百个产品,主要包括抗体、组织染色切片、FISH、CISH探针、qPCR&NGS试剂盒等,针对分子生物学、二代测序、组织学、原位杂交、流式细胞学等应用,所有这些诊断产品均拥有CE/IVD认证,可以确保临床应用中的准确性。在研究领域,Generon拥有上百万个产品,主要是针对分子生物学、NGS、2D、3D细胞培养、免疫检测、色谱、电泳等实验的抗体、ELISA试剂盒等。

 

Generon’s catalog includes several hundred products for diagnosis and medical biology. Our products cover a wide range of applications and field of medical diagnostics. We want to offer you all the products you need to move your projects forward. Applications: molecular biology, NGS, histology, in situ hybridization, flow cytometry ... Types of products: Antibodies, tissue stains, probes for FISH and CISH, qPCR and NGS kits, culture media.... All our medical diagnostic products are CE / IVD-certified (In Vitro Diagnostic) to ensure quality and follow-up for reliable results in diagnosis and choosing the right treatment.

Generon’s catalog includes millions of products for research in the life sciences. Our products cover a wide range of applications and research areas. We want to offer you all the products you need to move your projects forward. Applications: Molecular biology, NGS, 2D and 3D cell culture, immunoassays, chromatography, electrophoresis ... Types of products: Antibodies, ELISA kits, PCR Enzymes, particles, tetramers, disinfectants ...

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更多详情请联系 

艾美捷科技有限公司

全国服务热线:400-6800-868

邮箱:sales@amyjet.com

网站:www.amyjet.com

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艾美捷科技代理VisualProtein品牌。

VisualProtein成立于2005年,致力于通过提供创新的科研产品与服务推动生物领域发展。凭借在蛋白质组学、免疫学及细胞学领域的专业深耕,不断拓宽科学研究的可能性边界。


Visual Protein的产品包括:

分类品名货号
ProteomicsWestern Blot Tool BoxBOX12
ProteomicsWestern Blot Tool Box with LuminolPen(LH03-10)BOX12-03
ProteomicsBlockPRO™ Blocking BufferBP01-1L
ProteomicsBlockPRO™ Protein-Free Blocking BufferBF01
ProteomicsBlockPRO™ 1 Min Protein-Free Blocking BufferBM01
ProteomicsLuminolPen™, HRP systemLH03
ProteomicsLumiFlash™ Prime Chemiluminescent Substrate, HRP SystemLF01-500
ProteomicsLumiFlash™ Ultima Chemiluminescent Substrate, HRP SystemLF08-500
ProteomicsLumiFlash™ Infinity Chemiluminescent Substrate, HRP SystemLF16-500
ProteomicsLumiFlash™ Femto Chemiluminescent substrate, HRP SystemLF24-100
ProteomicsExtractPRO™ Protein Extraction ReagentEP05-30
ProteomicsRIPA Cell Lysis BufferRP05
ProteomicsDual-Range™ BCA Protein Assay KitBC03-500
ProteomicsDual-Range™ Bradford Reagent (1X)BR01-500
ProteomicsDual-Range™ Bradford Reagent (5X)BR05-500
ProteomicsDual-Range™ Bradford Protein Assay Kit (5X)BR05-500-K
ProteomicsVisPRO™ Blue-One Protein StainVB01-500
ProteomicsVisPRO™ 5 Minute Protein Stain KitVP01
Proteomics6X Laemmli SDS Sample Buffer, non-reducing(without beta-mercaptoethanol)SBN06-15
Proteomics6X Laemmli SDS Sample Buffer, reducing(with beta-mercaptoethanol)SBR06-15
Immunoassay bufferImmunoEX immunoassayDevelopment Kit(TBST)IEX001
Immunoassay bufferImmunoEX ImmunoassayDevelopment Kit (TBS)IEX002
Immunoassay bufferImmunoEX TBST BufferIE01-500
Immunoassay bufferImmunoEX TBS BufferIE02-500
Immunoassay buffermmunoEX Protein-BasedImmunoassay Buffer(TBSTIE03-500
Immunoassay bufferImmunoEX Protein-Based lmmunoassay Buffer (TBS)IE04-500
Immunoassay bufferImmunoEX Protein-Free Immunoassay Buffer(TBSTIE05-500
Immunoassay bufferImmunoEX Protein-Free Immunoassay Buffer (TBS)IE06-500
SupplementCytoMore Cell RescueSupplementCTO1-1BT
SupplementHybriMore™ Hybridoma Culture Supplement*HB01-1L
BufferPBS Buffer, 10XPBS10-1L
BufferPBS Tween-20 Buffer, 10XPBST10-1L
BufferTBS Buffer, 10XTBS10-1L
BufferTBS Tween-20 Buffer, 10XTBST10-1L
BufferTBS Tween-20 Buffer, 25XTBST200P
BufferSDS-PAGE Running Buffer, 10XRB10-1L
BufferSDS-PAGE Running Buffer, powder packRB500P
BufferWestern Blot Transfer Buffer, 10XWTB10-1L
BufferWestern Blot Transfer Buffer, powder packWTB500P



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